Antara

Antara Brand names, Antara Analogs

Antara Brand Names Mixture

No information avaliable

Antara Chemical_Formula

C₂₀H₂₁ClO₄

Antara RX_link

http://www.rxlist.com/cgi/generic3/fenofibrate.htm

Antara fda sheet

Antara FDA

Antara msds (material safety sheet)

Antara MSDS

Antara Synthesis Reference

No information avaliable

Antara Molecular Weight

360.831 g/mol

Antara Melting Point

80.5 °C

Antara H₂O Solubility

0.25mg/ml at 25 °C

Antara State

Solid

Antara LogP

5.575

Antara Dosage Forms

Capsule; Tablet

Antara Indication

For use as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb)

Antara Pharmacology

Fenofibrate is a lipid regulating agent indicated as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb). Fenofibrate is also indicated as adjunctive therapy to diet for treatment of adult patients with hypertriglyceridemia (Fredrickson Types IV and V hyperlipidemia). Fenofibric acid, the active metabolite of Fenofibrate, produces reductions in total cholesterol, LDL cholesterol, apolipoprotein B, total triglycerides and triglyceride rich lipoprotein (VLDL) in treated patients. In addition, treatment with fenofibrate results in increases in high density lipoprotein (HDL) and apoproteins apoAI and apoAII.

Antara Absorption

Fenofibrate is well absorbed from the gastrointestinal tract. After absorption, fenofibrate is mainly excreted in the urine in the form of metabolites, primarily fenofibric acid and fenofibric acid glucuronide

Antara side effects and Toxicity

LD₅₀=1600 mg/kg (Oral, in mice); Investigated as a teratogen and reproductive hazard.

Antara Patient Information