Proctofene

Proctofene Brand names, Proctofene Analogs

Proctofene Brand Names Mixture

No information avaliable

Proctofene Chemical_Formula

C₂₀H₂₁ClO₄

Proctofene RX_link

http://www.rxlist.com/cgi/generic3/fenofibrate.htm

Proctofene fda sheet

Proctofene FDA

Proctofene msds (material safety sheet)

Proctofene MSDS

Proctofene Synthesis Reference

No information avaliable

Proctofene Molecular Weight

360.831 g/mol

Proctofene Melting Point

80.5 °C

Proctofene H₂O Solubility

0.25mg/ml at 25 °C

Proctofene State

Solid

Proctofene LogP

5.575

Proctofene Dosage Forms

Capsule; Tablet

Proctofene Indication

For use as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb)

Proctofene Pharmacology

Fenofibrate is a lipid regulating agent indicated as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb). Fenofibrate is also indicated as adjunctive therapy to diet for treatment of adult patients with hypertriglyceridemia (Fredrickson Types IV and V hyperlipidemia). Fenofibric acid, the active metabolite of Fenofibrate, produces reductions in total cholesterol, LDL cholesterol, apolipoprotein B, total triglycerides and triglyceride rich lipoprotein (VLDL) in treated patients. In addition, treatment with fenofibrate results in increases in high density lipoprotein (HDL) and apoproteins apoAI and apoAII.

Proctofene Absorption

Fenofibrate is well absorbed from the gastrointestinal tract. After absorption, fenofibrate is mainly excreted in the urine in the form of metabolites, primarily fenofibric acid and fenofibric acid glucuronide

Proctofene side effects and Toxicity

LD₅₀=1600 mg/kg (Oral, in mice); Investigated as a teratogen and reproductive hazard.

Proctofene Patient Information