Lipifen

Lipifen Brand names, Lipifen Analogs

Lipifen Brand Names Mixture

No information avaliable

Lipifen Chemical_Formula

C₂₀H₂₁ClO₄

Lipifen RX_link

http://www.rxlist.com/cgi/generic3/fenofibrate.htm

Lipifen fda sheet

Lipifen FDA

Lipifen msds (material safety sheet)

Lipifen MSDS

Lipifen Synthesis Reference

No information avaliable

Lipifen Molecular Weight

360.831 g/mol

Lipifen Melting Point

80.5 °C

Lipifen H₂O Solubility

0.25mg/ml at 25 °C

Lipifen State

Solid

Lipifen LogP

5.575

Lipifen Dosage Forms

Capsule; Tablet

Lipifen Indication

For use as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb)

Lipifen Pharmacology

Fenofibrate is a lipid regulating agent indicated as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb). Fenofibrate is also indicated as adjunctive therapy to diet for treatment of adult patients with hypertriglyceridemia (Fredrickson Types IV and V hyperlipidemia). Fenofibric acid, the active metabolite of Fenofibrate, produces reductions in total cholesterol, LDL cholesterol, apolipoprotein B, total triglycerides and triglyceride rich lipoprotein (VLDL) in treated patients. In addition, treatment with fenofibrate results in increases in high density lipoprotein (HDL) and apoproteins apoAI and apoAII.

Lipifen Absorption

Fenofibrate is well absorbed from the gastrointestinal tract. After absorption, fenofibrate is mainly excreted in the urine in the form of metabolites, primarily fenofibric acid and fenofibric acid glucuronide

Lipifen side effects and Toxicity

LD₅₀=1600 mg/kg (Oral, in mice); Investigated as a teratogen and reproductive hazard.

Lipifen Patient Information