Lipofene

Lipofene Brand names, Lipofene Analogs

Lipofene Brand Names Mixture

No information avaliable

Lipofene Chemical_Formula

C₂₀H₂₁ClO₄

Lipofene RX_link

http://www.rxlist.com/cgi/generic3/fenofibrate.htm

Lipofene fda sheet

Lipofene FDA

Lipofene msds (material safety sheet)

Lipofene MSDS

Lipofene Synthesis Reference

No information avaliable

Lipofene Molecular Weight

360.831 g/mol

Lipofene Melting Point

80.5 °C

Lipofene H₂O Solubility

0.25mg/ml at 25 °C

Lipofene State

Solid

Lipofene LogP

5.575

Lipofene Dosage Forms

Capsule; Tablet

Lipofene Indication

For use as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb)

Lipofene Pharmacology

Fenofibrate is a lipid regulating agent indicated as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb). Fenofibrate is also indicated as adjunctive therapy to diet for treatment of adult patients with hypertriglyceridemia (Fredrickson Types IV and V hyperlipidemia). Fenofibric acid, the active metabolite of Fenofibrate, produces reductions in total cholesterol, LDL cholesterol, apolipoprotein B, total triglycerides and triglyceride rich lipoprotein (VLDL) in treated patients. In addition, treatment with fenofibrate results in increases in high density lipoprotein (HDL) and apoproteins apoAI and apoAII.

Lipofene Absorption

Fenofibrate is well absorbed from the gastrointestinal tract. After absorption, fenofibrate is mainly excreted in the urine in the form of metabolites, primarily fenofibric acid and fenofibric acid glucuronide

Lipofene side effects and Toxicity

LD₅₀=1600 mg/kg (Oral, in mice); Investigated as a teratogen and reproductive hazard.

Lipofene Patient Information