Lipirex

Lipirex Brand names, Lipirex Analogs

Lipirex Brand Names Mixture

No information avaliable

Lipirex Chemical_Formula

C₂₀H₂₁ClO₄

Lipirex RX_link

http://www.rxlist.com/cgi/generic3/fenofibrate.htm

Lipirex fda sheet

Lipirex FDA

Lipirex msds (material safety sheet)

Lipirex MSDS

Lipirex Synthesis Reference

No information avaliable

Lipirex Molecular Weight

360.831 g/mol

Lipirex Melting Point

80.5 °C

Lipirex H₂O Solubility

0.25mg/ml at 25 °C

Lipirex State

Solid

Lipirex LogP

5.575

Lipirex Dosage Forms

Capsule; Tablet

Lipirex Indication

For use as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb)

Lipirex Pharmacology

Fenofibrate is a lipid regulating agent indicated as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb). Fenofibrate is also indicated as adjunctive therapy to diet for treatment of adult patients with hypertriglyceridemia (Fredrickson Types IV and V hyperlipidemia). Fenofibric acid, the active metabolite of Fenofibrate, produces reductions in total cholesterol, LDL cholesterol, apolipoprotein B, total triglycerides and triglyceride rich lipoprotein (VLDL) in treated patients. In addition, treatment with fenofibrate results in increases in high density lipoprotein (HDL) and apoproteins apoAI and apoAII.

Lipirex Absorption

Fenofibrate is well absorbed from the gastrointestinal tract. After absorption, fenofibrate is mainly excreted in the urine in the form of metabolites, primarily fenofibric acid and fenofibric acid glucuronide

Lipirex side effects and Toxicity

LD₅₀=1600 mg/kg (Oral, in mice); Investigated as a teratogen and reproductive hazard.

Lipirex Patient Information