Sedufen

Sedufen Brand names, Sedufen Analogs

Sedufen Brand Names Mixture

No information avaliable

Sedufen Chemical_Formula

C₂₀H₂₁ClO₄

Sedufen RX_link

http://www.rxlist.com/cgi/generic3/fenofibrate.htm

Sedufen fda sheet

Sedufen FDA

Sedufen msds (material safety sheet)

Sedufen MSDS

Sedufen Synthesis Reference

No information avaliable

Sedufen Molecular Weight

360.831 g/mol

Sedufen Melting Point

80.5 °C

Sedufen H₂O Solubility

0.25mg/ml at 25 °C

Sedufen State

Solid

Sedufen LogP

5.575

Sedufen Dosage Forms

Capsule; Tablet

Sedufen Indication

For use as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb)

Sedufen Pharmacology

Fenofibrate is a lipid regulating agent indicated as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb). Fenofibrate is also indicated as adjunctive therapy to diet for treatment of adult patients with hypertriglyceridemia (Fredrickson Types IV and V hyperlipidemia). Fenofibric acid, the active metabolite of Fenofibrate, produces reductions in total cholesterol, LDL cholesterol, apolipoprotein B, total triglycerides and triglyceride rich lipoprotein (VLDL) in treated patients. In addition, treatment with fenofibrate results in increases in high density lipoprotein (HDL) and apoproteins apoAI and apoAII.

Sedufen Absorption

Fenofibrate is well absorbed from the gastrointestinal tract. After absorption, fenofibrate is mainly excreted in the urine in the form of metabolites, primarily fenofibric acid and fenofibric acid glucuronide

Sedufen side effects and Toxicity

LD₅₀=1600 mg/kg (Oral, in mice); Investigated as a teratogen and reproductive hazard.

Sedufen Patient Information