Lipidil Supra
Brand names,
Lipidil Supra
Analogs
Lipidil Supra
Brand Names Mixture
Lipidil Supra
Chemical_Formula
C20H21ClO4
Lipidil Supra
RX_link
http://www.rxlist.com/cgi/generic3/fenofibrate.htm
Lipidil Supra
fda sheet
Lipidil Supra
msds (material safety sheet)
Lipidil Supra
Synthesis Reference
No information avaliable
Lipidil Supra
Molecular Weight
360.831 g/mol
Lipidil Supra
Melting Point
80.5 °C
Lipidil Supra
H2O Solubility
0.25mg/ml at 25 °C
Lipidil Supra
State
Solid
Lipidil Supra
LogP
5.575
Lipidil Supra
Dosage Forms
Capsule; Tablet
Lipidil Supra
Indication
For use as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb)
Lipidil Supra
Pharmacology
Fenofibrate is a lipid regulating agent indicated as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb). Fenofibrate is also indicated as adjunctive therapy to diet for treatment of adult patients with hypertriglyceridemia (Fredrickson Types IV and V hyperlipidemia). Fenofibric acid, the active metabolite of Fenofibrate, produces reductions in total cholesterol, LDL cholesterol, apolipoprotein B, total triglycerides and triglyceride rich lipoprotein (VLDL) in treated patients. In addition, treatment with fenofibrate results in increases in high density lipoprotein (HDL) and apoproteins apoAI and apoAII.
Lipidil Supra
Absorption
Fenofibrate is well absorbed from the gastrointestinal tract. After absorption, fenofibrate is mainly excreted in the urine in the form of metabolites, primarily fenofibric acid and fenofibric acid glucuronide
Lipidil Supra
side effects and Toxicity
LD50=1600 mg/kg (Oral, in mice); Investigated as a teratogen and reproductive hazard.
Lipidil Supra
Patient Information
No information avaliable
Lipidil Supra
Organisms Affected
Humans and other mammals