Finofibrate
Finofibrate Brand names, Finofibrate Analogs
- Ankebin
- Antara
- Elasterate
- Elasterin
- FNF
- Fenobrate
- Fenofibrate [Ban:Inn]
- Fenofibrato [Inn-Spanish]
- Fenofibratum [Inn-Latin]
- Fenogal
- Fenotard
- Finofibrate
- Lipanthyl
- Lipantil
- Lipidex
- Lipidil
- Lipidil Micro
- Lipidil Supra
- Lipifen
- Lipirex
- Lipoclar
- Lipofene
- Liposit
- Lipsin
- Lofibra
- Luxacor
- Nolipax
- Procetofen
- Proctofene
- Protolipan
- Secalip
- Sedufen
- Tricor
- Triglide
Finofibrate Brand Names Mixture
- No information avaliable
Finofibrate Chemical_Formula
C20H21ClO4
Finofibrate RX_link
http://www.rxlist.com/cgi/generic3/fenofibrate.htm
Finofibrate fda sheet
Finofibrate msds (material safety sheet)
Finofibrate Synthesis Reference
No information avaliable
Finofibrate Molecular Weight
360.831 g/mol
Finofibrate Melting Point
80.5 °C
Finofibrate H2O Solubility
0.25mg/ml at 25 °C
Finofibrate State
Solid
Finofibrate LogP
5.575
Finofibrate Dosage Forms
Capsule; Tablet
Finofibrate Indication
For use as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb)
Finofibrate Pharmacology
Fenofibrate is a lipid regulating agent indicated as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb). Fenofibrate is also indicated as adjunctive therapy to diet for treatment of adult patients with hypertriglyceridemia (Fredrickson Types IV and V hyperlipidemia). Fenofibric acid, the active metabolite of Fenofibrate, produces reductions in total cholesterol, LDL cholesterol, apolipoprotein B, total triglycerides and triglyceride rich lipoprotein (VLDL) in treated patients. In addition, treatment with fenofibrate results in increases in high density lipoprotein (HDL) and apoproteins apoAI and apoAII.
Finofibrate Absorption
Fenofibrate is well absorbed from the gastrointestinal tract. After absorption, fenofibrate is mainly excreted in the urine in the form of metabolites, primarily fenofibric acid and fenofibric acid glucuronide
Finofibrate side effects and Toxicity
LD50=1600 mg/kg (Oral, in mice); Investigated as a teratogen and reproductive hazard.
Finofibrate Patient Information
No information avaliable
Finofibrate Organisms Affected
Humans and other mammals
