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Diaminopyritamin Brand names, Diaminopyritamin Analogs

Diaminopyritamin Brand Names Mixture

  • Fansidar Tablets (Pyrimethamine + Sulfadoxine)
  • Quinnoxine-S (Pyrimethamine + Sulfaquinoxaline)
  • Sulfaquinoxaline-S Liq (Pyrimethamine + Sulfaquinoxaline)

Diaminopyritamin Chemical_Formula


Diaminopyritamin RX_link


Diaminopyritamin fda sheet

Diaminopyritamin FDA

Diaminopyritamin msds (material safety sheet)

Diaminopyritamin MSDS

Diaminopyritamin Synthesis Reference

Russel, Hitchings, J. Am. Chem. Soc. 73, 3763 (1951); Hitchings et al., U.S. pats. 2,576,939; 2,579,259, and 2,602,794 (1951 and 1952 to Burroughs Wellcome); Jacob, U.S. pat 2,680,740 (1954 to Rhone-Poulenc)

Diaminopyritamin Molecular Weight

248.711 g/mol

Diaminopyritamin Melting Point

233.5 oC

Diaminopyritamin H2O Solubility

121 mg/L

Diaminopyritamin State


Diaminopyritamin LogP


Diaminopyritamin Dosage Forms


Diaminopyritamin Indication

For the treatment of toxoplasmosis and acute malaria; For the prevention of malaria in areas non-resistant to pyrimethamine

Diaminopyritamin Pharmacology

Pyrimethamine is an antiparasitic compound commonly used as an adjunct in the treatment of uncomplicated, chloroquine resistant, P. falciparum malaria. Pyrimethamine is a folic acid antagonist and the rationale for its therapeutic action is based on the differential requirement between host and parasite for nucleic acid precursors involved in growth. This activity is highly selective against plasmodia and Toxoplasma gondii. Pyrimethamine possesses blood schizonticidal and some tissue schizonticidal activity against malaria parasites of humans. However, the 4-amino-quinoline compounds are more effective against the erythrocytic schizonts. It does not destroy gametocytes, but arrests sporogony in the mosquito. The action of pyrimethamine against Toxoplasma gondii is greatly enhanced when used in conjunction with sulfonamides.

Diaminopyritamin Absorption

Well absorbed with peak levels occurring between 2 to 6 hours following administration

Diaminopyritamin side effects and Toxicity

No information avaliable

Diaminopyritamin Patient Information

Diaminopyritamin Organisms Affected