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Ethylpyrimidine Brand names, Ethylpyrimidine Analogs

Ethylpyrimidine Brand Names Mixture

  • Fansidar Tablets (Pyrimethamine + Sulfadoxine)
  • Quinnoxine-S (Pyrimethamine + Sulfaquinoxaline)
  • Sulfaquinoxaline-S Liq (Pyrimethamine + Sulfaquinoxaline)

Ethylpyrimidine Chemical_Formula


Ethylpyrimidine RX_link

Ethylpyrimidine fda sheet

Ethylpyrimidine FDA

Ethylpyrimidine msds (material safety sheet)

Ethylpyrimidine MSDS

Ethylpyrimidine Synthesis Reference

Russel, Hitchings, J. Am. Chem. Soc. 73, 3763 (1951); Hitchings et al., U.S. pats. 2,576,939; 2,579,259, and 2,602,794 (1951 and 1952 to Burroughs Wellcome); Jacob, U.S. pat 2,680,740 (1954 to Rhone-Poulenc)

Ethylpyrimidine Molecular Weight

248.711 g/mol

Ethylpyrimidine Melting Point

233.5 oC

Ethylpyrimidine H2O Solubility

121 mg/L

Ethylpyrimidine State


Ethylpyrimidine LogP


Ethylpyrimidine Dosage Forms


Ethylpyrimidine Indication

For the treatment of toxoplasmosis and acute malaria; For the prevention of malaria in areas non-resistant to pyrimethamine

Ethylpyrimidine Pharmacology

Pyrimethamine is an antiparasitic compound commonly used as an adjunct in the treatment of uncomplicated, chloroquine resistant, P. falciparum malaria. Pyrimethamine is a folic acid antagonist and the rationale for its therapeutic action is based on the differential requirement between host and parasite for nucleic acid precursors involved in growth. This activity is highly selective against plasmodia and Toxoplasma gondii. Pyrimethamine possesses blood schizonticidal and some tissue schizonticidal activity against malaria parasites of humans. However, the 4-amino-quinoline compounds are more effective against the erythrocytic schizonts. It does not destroy gametocytes, but arrests sporogony in the mosquito. The action of pyrimethamine against Toxoplasma gondii is greatly enhanced when used in conjunction with sulfonamides.

Ethylpyrimidine Absorption

Well absorbed with peak levels occurring between 2 to 6 hours following administration

Ethylpyrimidine side effects and Toxicity

No information avaliable

Ethylpyrimidine Patient Information

Ethylpyrimidine Organisms Affected