Malocid en es it fr

Malocid Brand names, Malocid Analogs

Malocid Brand Names Mixture

  • Fansidar Tablets (Pyrimethamine + Sulfadoxine)
  • Quinnoxine-S (Pyrimethamine + Sulfaquinoxaline)
  • Sulfaquinoxaline-S Liq (Pyrimethamine + Sulfaquinoxaline)

Malocid Chemical_Formula


Malocid RX_link

Malocid fda sheet

Malocid FDA

Malocid msds (material safety sheet)

Malocid MSDS

Malocid Synthesis Reference

Russel, Hitchings, J. Am. Chem. Soc. 73, 3763 (1951); Hitchings et al., U.S. pats. 2,576,939; 2,579,259, and 2,602,794 (1951 and 1952 to Burroughs Wellcome); Jacob, U.S. pat 2,680,740 (1954 to Rhone-Poulenc)

Malocid Molecular Weight

248.711 g/mol

Malocid Melting Point

233.5 oC

Malocid H2O Solubility

121 mg/L

Malocid State


Malocid LogP


Malocid Dosage Forms


Malocid Indication

For the treatment of toxoplasmosis and acute malaria; For the prevention of malaria in areas non-resistant to pyrimethamine

Malocid Pharmacology

Pyrimethamine is an antiparasitic compound commonly used as an adjunct in the treatment of uncomplicated, chloroquine resistant, P. falciparum malaria. Pyrimethamine is a folic acid antagonist and the rationale for its therapeutic action is based on the differential requirement between host and parasite for nucleic acid precursors involved in growth. This activity is highly selective against plasmodia and Toxoplasma gondii. Pyrimethamine possesses blood schizonticidal and some tissue schizonticidal activity against malaria parasites of humans. However, the 4-amino-quinoline compounds are more effective against the erythrocytic schizonts. It does not destroy gametocytes, but arrests sporogony in the mosquito. The action of pyrimethamine against Toxoplasma gondii is greatly enhanced when used in conjunction with sulfonamides.

Malocid Absorption

Well absorbed with peak levels occurring between 2 to 6 hours following administration

Malocid side effects and Toxicity

No information avaliable

Malocid Patient Information

Malocid Organisms Affected