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Fansidar Brand names, Fansidar Analogs

Fansidar Brand Names Mixture

  • Fansidar Tablets (Pyrimethamine + Sulfadoxine)
  • Quinnoxine-S (Pyrimethamine + Sulfaquinoxaline)
  • Sulfaquinoxaline-S Liq (Pyrimethamine + Sulfaquinoxaline)

Fansidar Chemical_Formula


Fansidar RX_link

Fansidar fda sheet

Fansidar FDA

Fansidar msds (material safety sheet)

Fansidar MSDS

Fansidar Synthesis Reference

Russel, Hitchings, J. Am. Chem. Soc. 73, 3763 (1951); Hitchings et al., U.S. pats. 2,576,939; 2,579,259, and 2,602,794 (1951 and 1952 to Burroughs Wellcome); Jacob, U.S. pat 2,680,740 (1954 to Rhone-Poulenc)

Fansidar Molecular Weight

248.711 g/mol

Fansidar Melting Point

233.5 oC

Fansidar H2O Solubility

121 mg/L

Fansidar State


Fansidar LogP


Fansidar Dosage Forms


Fansidar Indication

For the treatment of toxoplasmosis and acute malaria; For the prevention of malaria in areas non-resistant to pyrimethamine

Fansidar Pharmacology

Pyrimethamine is an antiparasitic compound commonly used as an adjunct in the treatment of uncomplicated, chloroquine resistant, P. falciparum malaria. Pyrimethamine is a folic acid antagonist and the rationale for its therapeutic action is based on the differential requirement between host and parasite for nucleic acid precursors involved in growth. This activity is highly selective against plasmodia and Toxoplasma gondii. Pyrimethamine possesses blood schizonticidal and some tissue schizonticidal activity against malaria parasites of humans. However, the 4-amino-quinoline compounds are more effective against the erythrocytic schizonts. It does not destroy gametocytes, but arrests sporogony in the mosquito. The action of pyrimethamine against Toxoplasma gondii is greatly enhanced when used in conjunction with sulfonamides.

Fansidar Absorption

Well absorbed with peak levels occurring between 2 to 6 hours following administration

Fansidar side effects and Toxicity

No information avaliable

Fansidar Patient Information

Fansidar Organisms Affected