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Tindurin Brand names, Tindurin Analogs

Tindurin Brand Names Mixture

  • Fansidar Tablets (Pyrimethamine + Sulfadoxine)
  • Quinnoxine-S (Pyrimethamine + Sulfaquinoxaline)
  • Sulfaquinoxaline-S Liq (Pyrimethamine + Sulfaquinoxaline)

Tindurin Chemical_Formula


Tindurin RX_link


Tindurin fda sheet

Tindurin FDA

Tindurin msds (material safety sheet)

Tindurin MSDS

Tindurin Synthesis Reference

Russel, Hitchings, J. Am. Chem. Soc. 73, 3763 (1951); Hitchings et al., U.S. pats. 2,576,939; 2,579,259, and 2,602,794 (1951 and 1952 to Burroughs Wellcome); Jacob, U.S. pat 2,680,740 (1954 to Rhone-Poulenc)

Tindurin Molecular Weight

248.711 g/mol

Tindurin Melting Point

233.5 oC

Tindurin H2O Solubility

121 mg/L

Tindurin State


Tindurin LogP


Tindurin Dosage Forms


Tindurin Indication

For the treatment of toxoplasmosis and acute malaria; For the prevention of malaria in areas non-resistant to pyrimethamine

Tindurin Pharmacology

Pyrimethamine is an antiparasitic compound commonly used as an adjunct in the treatment of uncomplicated, chloroquine resistant, P. falciparum malaria. Pyrimethamine is a folic acid antagonist and the rationale for its therapeutic action is based on the differential requirement between host and parasite for nucleic acid precursors involved in growth. This activity is highly selective against plasmodia and Toxoplasma gondii. Pyrimethamine possesses blood schizonticidal and some tissue schizonticidal activity against malaria parasites of humans. However, the 4-amino-quinoline compounds are more effective against the erythrocytic schizonts. It does not destroy gametocytes, but arrests sporogony in the mosquito. The action of pyrimethamine against Toxoplasma gondii is greatly enhanced when used in conjunction with sulfonamides.

Tindurin Absorption

Well absorbed with peak levels occurring between 2 to 6 hours following administration

Tindurin side effects and Toxicity

No information avaliable

Tindurin Patient Information

Tindurin Organisms Affected