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Chloridyn Brand names, Chloridyn Analogs

Chloridyn Brand Names Mixture

  • Fansidar Tablets (Pyrimethamine + Sulfadoxine)
  • Quinnoxine-S (Pyrimethamine + Sulfaquinoxaline)
  • Sulfaquinoxaline-S Liq (Pyrimethamine + Sulfaquinoxaline)

Chloridyn Chemical_Formula


Chloridyn RX_link

Chloridyn fda sheet

Chloridyn FDA

Chloridyn msds (material safety sheet)

Chloridyn MSDS

Chloridyn Synthesis Reference

Russel, Hitchings, J. Am. Chem. Soc. 73, 3763 (1951); Hitchings et al., U.S. pats. 2,576,939; 2,579,259, and 2,602,794 (1951 and 1952 to Burroughs Wellcome); Jacob, U.S. pat 2,680,740 (1954 to Rhone-Poulenc)

Chloridyn Molecular Weight

248.711 g/mol

Chloridyn Melting Point

233.5 oC

Chloridyn H2O Solubility

121 mg/L

Chloridyn State


Chloridyn LogP


Chloridyn Dosage Forms


Chloridyn Indication

For the treatment of toxoplasmosis and acute malaria; For the prevention of malaria in areas non-resistant to pyrimethamine

Chloridyn Pharmacology

Pyrimethamine is an antiparasitic compound commonly used as an adjunct in the treatment of uncomplicated, chloroquine resistant, P. falciparum malaria. Pyrimethamine is a folic acid antagonist and the rationale for its therapeutic action is based on the differential requirement between host and parasite for nucleic acid precursors involved in growth. This activity is highly selective against plasmodia and Toxoplasma gondii. Pyrimethamine possesses blood schizonticidal and some tissue schizonticidal activity against malaria parasites of humans. However, the 4-amino-quinoline compounds are more effective against the erythrocytic schizonts. It does not destroy gametocytes, but arrests sporogony in the mosquito. The action of pyrimethamine against Toxoplasma gondii is greatly enhanced when used in conjunction with sulfonamides.

Chloridyn Absorption

Well absorbed with peak levels occurring between 2 to 6 hours following administration

Chloridyn side effects and Toxicity

No information avaliable

Chloridyn Patient Information

Chloridyn Organisms Affected