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Khloridin Brand names, Khloridin Analogs

Khloridin Brand Names Mixture

  • Fansidar Tablets (Pyrimethamine + Sulfadoxine)
  • Quinnoxine-S (Pyrimethamine + Sulfaquinoxaline)
  • Sulfaquinoxaline-S Liq (Pyrimethamine + Sulfaquinoxaline)

Khloridin Chemical_Formula


Khloridin RX_link

Khloridin fda sheet

Khloridin FDA

Khloridin msds (material safety sheet)

Khloridin MSDS

Khloridin Synthesis Reference

Russel, Hitchings, J. Am. Chem. Soc. 73, 3763 (1951); Hitchings et al., U.S. pats. 2,576,939; 2,579,259, and 2,602,794 (1951 and 1952 to Burroughs Wellcome); Jacob, U.S. pat 2,680,740 (1954 to Rhone-Poulenc)

Khloridin Molecular Weight

248.711 g/mol

Khloridin Melting Point

233.5 oC

Khloridin H2O Solubility

121 mg/L

Khloridin State


Khloridin LogP


Khloridin Dosage Forms


Khloridin Indication

For the treatment of toxoplasmosis and acute malaria; For the prevention of malaria in areas non-resistant to pyrimethamine

Khloridin Pharmacology

Pyrimethamine is an antiparasitic compound commonly used as an adjunct in the treatment of uncomplicated, chloroquine resistant, P. falciparum malaria. Pyrimethamine is a folic acid antagonist and the rationale for its therapeutic action is based on the differential requirement between host and parasite for nucleic acid precursors involved in growth. This activity is highly selective against plasmodia and Toxoplasma gondii. Pyrimethamine possesses blood schizonticidal and some tissue schizonticidal activity against malaria parasites of humans. However, the 4-amino-quinoline compounds are more effective against the erythrocytic schizonts. It does not destroy gametocytes, but arrests sporogony in the mosquito. The action of pyrimethamine against Toxoplasma gondii is greatly enhanced when used in conjunction with sulfonamides.

Khloridin Absorption

Well absorbed with peak levels occurring between 2 to 6 hours following administration

Khloridin side effects and Toxicity

No information avaliable

Khloridin Patient Information

Khloridin Organisms Affected