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Daraprime Brand names, Daraprime Analogs

Daraprime Brand Names Mixture

  • Fansidar Tablets (Pyrimethamine + Sulfadoxine)
  • Quinnoxine-S (Pyrimethamine + Sulfaquinoxaline)
  • Sulfaquinoxaline-S Liq (Pyrimethamine + Sulfaquinoxaline)

Daraprime Chemical_Formula


Daraprime RX_link


Daraprime fda sheet

Daraprime FDA

Daraprime msds (material safety sheet)

Daraprime MSDS

Daraprime Synthesis Reference

Russel, Hitchings, J. Am. Chem. Soc. 73, 3763 (1951); Hitchings et al., U.S. pats. 2,576,939; 2,579,259, and 2,602,794 (1951 and 1952 to Burroughs Wellcome); Jacob, U.S. pat 2,680,740 (1954 to Rhone-Poulenc)

Daraprime Molecular Weight

248.711 g/mol

Daraprime Melting Point

233.5 oC

Daraprime H2O Solubility

121 mg/L

Daraprime State


Daraprime LogP


Daraprime Dosage Forms


Daraprime Indication

For the treatment of toxoplasmosis and acute malaria; For the prevention of malaria in areas non-resistant to pyrimethamine

Daraprime Pharmacology

Pyrimethamine is an antiparasitic compound commonly used as an adjunct in the treatment of uncomplicated, chloroquine resistant, P. falciparum malaria. Pyrimethamine is a folic acid antagonist and the rationale for its therapeutic action is based on the differential requirement between host and parasite for nucleic acid precursors involved in growth. This activity is highly selective against plasmodia and Toxoplasma gondii. Pyrimethamine possesses blood schizonticidal and some tissue schizonticidal activity against malaria parasites of humans. However, the 4-amino-quinoline compounds are more effective against the erythrocytic schizonts. It does not destroy gametocytes, but arrests sporogony in the mosquito. The action of pyrimethamine against Toxoplasma gondii is greatly enhanced when used in conjunction with sulfonamides.

Daraprime Absorption

Well absorbed with peak levels occurring between 2 to 6 hours following administration

Daraprime side effects and Toxicity

No information avaliable

Daraprime Patient Information

Daraprime Organisms Affected