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Chloridin Brand names, Chloridin Analogs

Chloridin Brand Names Mixture

  • Fansidar Tablets (Pyrimethamine + Sulfadoxine)
  • Quinnoxine-S (Pyrimethamine + Sulfaquinoxaline)
  • Sulfaquinoxaline-S Liq (Pyrimethamine + Sulfaquinoxaline)

Chloridin Chemical_Formula


Chloridin RX_link

Chloridin fda sheet

Chloridin FDA

Chloridin msds (material safety sheet)

Chloridin MSDS

Chloridin Synthesis Reference

Russel, Hitchings, J. Am. Chem. Soc. 73, 3763 (1951); Hitchings et al., U.S. pats. 2,576,939; 2,579,259, and 2,602,794 (1951 and 1952 to Burroughs Wellcome); Jacob, U.S. pat 2,680,740 (1954 to Rhone-Poulenc)

Chloridin Molecular Weight

248.711 g/mol

Chloridin Melting Point

233.5 oC

Chloridin H2O Solubility

121 mg/L

Chloridin State


Chloridin LogP


Chloridin Dosage Forms


Chloridin Indication

For the treatment of toxoplasmosis and acute malaria; For the prevention of malaria in areas non-resistant to pyrimethamine

Chloridin Pharmacology

Pyrimethamine is an antiparasitic compound commonly used as an adjunct in the treatment of uncomplicated, chloroquine resistant, P. falciparum malaria. Pyrimethamine is a folic acid antagonist and the rationale for its therapeutic action is based on the differential requirement between host and parasite for nucleic acid precursors involved in growth. This activity is highly selective against plasmodia and Toxoplasma gondii. Pyrimethamine possesses blood schizonticidal and some tissue schizonticidal activity against malaria parasites of humans. However, the 4-amino-quinoline compounds are more effective against the erythrocytic schizonts. It does not destroy gametocytes, but arrests sporogony in the mosquito. The action of pyrimethamine against Toxoplasma gondii is greatly enhanced when used in conjunction with sulfonamides.

Chloridin Absorption

Well absorbed with peak levels occurring between 2 to 6 hours following administration

Chloridin side effects and Toxicity

No information avaliable

Chloridin Patient Information

Chloridin Organisms Affected