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Erbaprelina Brand names, Erbaprelina Analogs

Erbaprelina Brand Names Mixture

  • Fansidar Tablets (Pyrimethamine + Sulfadoxine)
  • Quinnoxine-S (Pyrimethamine + Sulfaquinoxaline)
  • Sulfaquinoxaline-S Liq (Pyrimethamine + Sulfaquinoxaline)

Erbaprelina Chemical_Formula


Erbaprelina RX_link

Erbaprelina fda sheet

Erbaprelina FDA

Erbaprelina msds (material safety sheet)

Erbaprelina MSDS

Erbaprelina Synthesis Reference

Russel, Hitchings, J. Am. Chem. Soc. 73, 3763 (1951); Hitchings et al., U.S. pats. 2,576,939; 2,579,259, and 2,602,794 (1951 and 1952 to Burroughs Wellcome); Jacob, U.S. pat 2,680,740 (1954 to Rhone-Poulenc)

Erbaprelina Molecular Weight

248.711 g/mol

Erbaprelina Melting Point

233.5 oC

Erbaprelina H2O Solubility

121 mg/L

Erbaprelina State


Erbaprelina LogP


Erbaprelina Dosage Forms


Erbaprelina Indication

For the treatment of toxoplasmosis and acute malaria; For the prevention of malaria in areas non-resistant to pyrimethamine

Erbaprelina Pharmacology

Pyrimethamine is an antiparasitic compound commonly used as an adjunct in the treatment of uncomplicated, chloroquine resistant, P. falciparum malaria. Pyrimethamine is a folic acid antagonist and the rationale for its therapeutic action is based on the differential requirement between host and parasite for nucleic acid precursors involved in growth. This activity is highly selective against plasmodia and Toxoplasma gondii. Pyrimethamine possesses blood schizonticidal and some tissue schizonticidal activity against malaria parasites of humans. However, the 4-amino-quinoline compounds are more effective against the erythrocytic schizonts. It does not destroy gametocytes, but arrests sporogony in the mosquito. The action of pyrimethamine against Toxoplasma gondii is greatly enhanced when used in conjunction with sulfonamides.

Erbaprelina Absorption

Well absorbed with peak levels occurring between 2 to 6 hours following administration

Erbaprelina side effects and Toxicity

No information avaliable

Erbaprelina Patient Information

Erbaprelina Organisms Affected