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Urografin acid Brand names, Urografin acid Analogs

Urografin acid Brand Names Mixture

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Urografin acid Chemical_Formula


Urografin acid RX_link

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Urografin acid fda sheet

Urografin acid msds (material safety sheet)

Urografin acid Synthesis Reference

No information avaliable

Urografin acid Molecular Weight

241.247 g/mol

Urografin acid Melting Point

250-255 oC (hydrochloride salt)

Urografin acid H2O Solubility

>20 mg/mL (dichloride salt)

Urografin acid State


Urografin acid LogP


Urografin acid Dosage Forms

No information avaliable

Urografin acid Indication

For the treatment of tetrahydrobiopterin (BH4) deficiency.

Urografin acid Pharmacology

Tetrahydrobiopterin (BH4) is used to convert several amino acids, including phenylalanine, to other essential molecules in the body including neurotransmitters. Tetrahydrobiopterin deficiency can be caused by mutations in GTP cyclohydrolase 1 (GCH1), 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (PCBD1), 6-pyruvoyltetrahydropterin synthase (PTS), and quinoid dihydropteridine reductase (QDPR) genes. These genes make the enzymes that are critical for producing and recycling tetrahydrobiopterin. If one of the enzymes fails to function correctly because of a gene mutation, little or no tetrahydrobiopterin is produced. As a result, phenylalanine from the diet builds up in the bloodstream and other tissues and can damage nerve cells in the brain. High levels of phenylalanine can result in signs and symptoms ranging from temporary low muscle tone to mental retardation, movement disorders, difficulty swallowing, seizures, behavioral problems, progressive problems with development, and an inability to control body temperature.

Urografin acid Absorption

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Urografin acid side effects and Toxicity

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Urografin acid Patient Information

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Urografin acid Organisms Affected

Humans and other mammals