Renografin 76 en es it fr

Renografin 76 Brand names, Renografin 76 Analogs

Renografin 76 Brand Names Mixture

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Renografin 76 Chemical_Formula


Renografin 76 RX_link

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Renografin 76 fda sheet

Renografin 76 msds (material safety sheet)

Renografin 76 Synthesis Reference

No information avaliable

Renografin 76 Molecular Weight

241.247 g/mol

Renografin 76 Melting Point

250-255 oC (hydrochloride salt)

Renografin 76 H2O Solubility

>20 mg/mL (dichloride salt)

Renografin 76 State


Renografin 76 LogP


Renografin 76 Dosage Forms

No information avaliable

Renografin 76 Indication

For the treatment of tetrahydrobiopterin (BH4) deficiency.

Renografin 76 Pharmacology

Tetrahydrobiopterin (BH4) is used to convert several amino acids, including phenylalanine, to other essential molecules in the body including neurotransmitters. Tetrahydrobiopterin deficiency can be caused by mutations in GTP cyclohydrolase 1 (GCH1), 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (PCBD1), 6-pyruvoyltetrahydropterin synthase (PTS), and quinoid dihydropteridine reductase (QDPR) genes. These genes make the enzymes that are critical for producing and recycling tetrahydrobiopterin. If one of the enzymes fails to function correctly because of a gene mutation, little or no tetrahydrobiopterin is produced. As a result, phenylalanine from the diet builds up in the bloodstream and other tissues and can damage nerve cells in the brain. High levels of phenylalanine can result in signs and symptoms ranging from temporary low muscle tone to mental retardation, movement disorders, difficulty swallowing, seizures, behavioral problems, progressive problems with development, and an inability to control body temperature.

Renografin 76 Absorption

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Renografin 76 side effects and Toxicity

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Renografin 76 Patient Information

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Renografin 76 Organisms Affected

Humans and other mammals