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Diatriazoate Brand names, Diatriazoate Analogs

Diatriazoate Brand Names Mixture

  • No information avaliable

Diatriazoate Chemical_Formula


Diatriazoate RX_link

No information avaliable

Diatriazoate fda sheet

Diatriazoate msds (material safety sheet)

Diatriazoate Synthesis Reference

No information avaliable

Diatriazoate Molecular Weight

241.247 g/mol

Diatriazoate Melting Point

250-255 oC (hydrochloride salt)

Diatriazoate H2O Solubility

>20 mg/mL (dichloride salt)

Diatriazoate State


Diatriazoate LogP


Diatriazoate Dosage Forms

No information avaliable

Diatriazoate Indication

For the treatment of tetrahydrobiopterin (BH4) deficiency.

Diatriazoate Pharmacology

Tetrahydrobiopterin (BH4) is used to convert several amino acids, including phenylalanine, to other essential molecules in the body including neurotransmitters. Tetrahydrobiopterin deficiency can be caused by mutations in GTP cyclohydrolase 1 (GCH1), 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (PCBD1), 6-pyruvoyltetrahydropterin synthase (PTS), and quinoid dihydropteridine reductase (QDPR) genes. These genes make the enzymes that are critical for producing and recycling tetrahydrobiopterin. If one of the enzymes fails to function correctly because of a gene mutation, little or no tetrahydrobiopterin is produced. As a result, phenylalanine from the diet builds up in the bloodstream and other tissues and can damage nerve cells in the brain. High levels of phenylalanine can result in signs and symptoms ranging from temporary low muscle tone to mental retardation, movement disorders, difficulty swallowing, seizures, behavioral problems, progressive problems with development, and an inability to control body temperature.

Diatriazoate Absorption

No information avaliable

Diatriazoate side effects and Toxicity

No information avaliable

Diatriazoate Patient Information

No information avaliable

Diatriazoate Organisms Affected

Humans and other mammals