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Diatrizoesaure Brand names, Diatrizoesaure Analogs

Diatrizoesaure Brand Names Mixture

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Diatrizoesaure Chemical_Formula


Diatrizoesaure RX_link

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Diatrizoesaure fda sheet

Diatrizoesaure msds (material safety sheet)

Diatrizoesaure Synthesis Reference

No information avaliable

Diatrizoesaure Molecular Weight

241.247 g/mol

Diatrizoesaure Melting Point

250-255 oC (hydrochloride salt)

Diatrizoesaure H2O Solubility

>20 mg/mL (dichloride salt)

Diatrizoesaure State


Diatrizoesaure LogP


Diatrizoesaure Dosage Forms

No information avaliable

Diatrizoesaure Indication

For the treatment of tetrahydrobiopterin (BH4) deficiency.

Diatrizoesaure Pharmacology

Tetrahydrobiopterin (BH4) is used to convert several amino acids, including phenylalanine, to other essential molecules in the body including neurotransmitters. Tetrahydrobiopterin deficiency can be caused by mutations in GTP cyclohydrolase 1 (GCH1), 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (PCBD1), 6-pyruvoyltetrahydropterin synthase (PTS), and quinoid dihydropteridine reductase (QDPR) genes. These genes make the enzymes that are critical for producing and recycling tetrahydrobiopterin. If one of the enzymes fails to function correctly because of a gene mutation, little or no tetrahydrobiopterin is produced. As a result, phenylalanine from the diet builds up in the bloodstream and other tissues and can damage nerve cells in the brain. High levels of phenylalanine can result in signs and symptoms ranging from temporary low muscle tone to mental retardation, movement disorders, difficulty swallowing, seizures, behavioral problems, progressive problems with development, and an inability to control body temperature.

Diatrizoesaure Absorption

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Diatrizoesaure side effects and Toxicity

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Diatrizoesaure Patient Information

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Diatrizoesaure Organisms Affected

Humans and other mammals