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Diatrizoesaure Brand names, Diatrizoesaure Analogs

Diatrizoesaure Brand Names Mixture

  • No information avaliable

Diatrizoesaure Chemical_Formula

C9H15N5O3

Diatrizoesaure RX_link

No information avaliable

Diatrizoesaure fda sheet

Diatrizoesaure msds (material safety sheet)

Diatrizoesaure Synthesis Reference

No information avaliable

Diatrizoesaure Molecular Weight

241.247 g/mol

Diatrizoesaure Melting Point

250-255 oC (hydrochloride salt)

Diatrizoesaure H2O Solubility

>20 mg/mL (dichloride salt)

Diatrizoesaure State

Solid

Diatrizoesaure LogP

-1.783

Diatrizoesaure Dosage Forms

No information avaliable

Diatrizoesaure Indication

For the treatment of tetrahydrobiopterin (BH4) deficiency.

Diatrizoesaure Pharmacology

Tetrahydrobiopterin (BH4) is used to convert several amino acids, including phenylalanine, to other essential molecules in the body including neurotransmitters. Tetrahydrobiopterin deficiency can be caused by mutations in GTP cyclohydrolase 1 (GCH1), 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (PCBD1), 6-pyruvoyltetrahydropterin synthase (PTS), and quinoid dihydropteridine reductase (QDPR) genes. These genes make the enzymes that are critical for producing and recycling tetrahydrobiopterin. If one of the enzymes fails to function correctly because of a gene mutation, little or no tetrahydrobiopterin is produced. As a result, phenylalanine from the diet builds up in the bloodstream and other tissues and can damage nerve cells in the brain. High levels of phenylalanine can result in signs and symptoms ranging from temporary low muscle tone to mental retardation, movement disorders, difficulty swallowing, seizures, behavioral problems, progressive problems with development, and an inability to control body temperature.

Diatrizoesaure Absorption

No information avaliable

Diatrizoesaure side effects and Toxicity

No information avaliable

Diatrizoesaure Patient Information

No information avaliable

Diatrizoesaure Organisms Affected

Humans and other mammals