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Diatrizoic acid Brand names, Diatrizoic acid Analogs

Diatrizoic acid Brand Names Mixture

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Diatrizoic acid Chemical_Formula


Diatrizoic acid RX_link

No information avaliable

Diatrizoic acid fda sheet

Diatrizoic acid msds (material safety sheet)

Diatrizoic acid Synthesis Reference

No information avaliable

Diatrizoic acid Molecular Weight

241.247 g/mol

Diatrizoic acid Melting Point

250-255 oC (hydrochloride salt)

Diatrizoic acid H2O Solubility

>20 mg/mL (dichloride salt)

Diatrizoic acid State


Diatrizoic acid LogP


Diatrizoic acid Dosage Forms

No information avaliable

Diatrizoic acid Indication

For the treatment of tetrahydrobiopterin (BH4) deficiency.

Diatrizoic acid Pharmacology

Tetrahydrobiopterin (BH4) is used to convert several amino acids, including phenylalanine, to other essential molecules in the body including neurotransmitters. Tetrahydrobiopterin deficiency can be caused by mutations in GTP cyclohydrolase 1 (GCH1), 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (PCBD1), 6-pyruvoyltetrahydropterin synthase (PTS), and quinoid dihydropteridine reductase (QDPR) genes. These genes make the enzymes that are critical for producing and recycling tetrahydrobiopterin. If one of the enzymes fails to function correctly because of a gene mutation, little or no tetrahydrobiopterin is produced. As a result, phenylalanine from the diet builds up in the bloodstream and other tissues and can damage nerve cells in the brain. High levels of phenylalanine can result in signs and symptoms ranging from temporary low muscle tone to mental retardation, movement disorders, difficulty swallowing, seizures, behavioral problems, progressive problems with development, and an inability to control body temperature.

Diatrizoic acid Absorption

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Diatrizoic acid side effects and Toxicity

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Diatrizoic acid Patient Information

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Diatrizoic acid Organisms Affected

Humans and other mammals