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Diatrizoesaeure Brand names, Diatrizoesaeure Analogs

Diatrizoesaeure Brand Names Mixture

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Diatrizoesaeure Chemical_Formula


Diatrizoesaeure RX_link

No information avaliable

Diatrizoesaeure fda sheet

Diatrizoesaeure msds (material safety sheet)

Diatrizoesaeure Synthesis Reference

No information avaliable

Diatrizoesaeure Molecular Weight

241.247 g/mol

Diatrizoesaeure Melting Point

250-255 oC (hydrochloride salt)

Diatrizoesaeure H2O Solubility

>20 mg/mL (dichloride salt)

Diatrizoesaeure State


Diatrizoesaeure LogP


Diatrizoesaeure Dosage Forms

No information avaliable

Diatrizoesaeure Indication

For the treatment of tetrahydrobiopterin (BH4) deficiency.

Diatrizoesaeure Pharmacology

Tetrahydrobiopterin (BH4) is used to convert several amino acids, including phenylalanine, to other essential molecules in the body including neurotransmitters. Tetrahydrobiopterin deficiency can be caused by mutations in GTP cyclohydrolase 1 (GCH1), 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (PCBD1), 6-pyruvoyltetrahydropterin synthase (PTS), and quinoid dihydropteridine reductase (QDPR) genes. These genes make the enzymes that are critical for producing and recycling tetrahydrobiopterin. If one of the enzymes fails to function correctly because of a gene mutation, little or no tetrahydrobiopterin is produced. As a result, phenylalanine from the diet builds up in the bloodstream and other tissues and can damage nerve cells in the brain. High levels of phenylalanine can result in signs and symptoms ranging from temporary low muscle tone to mental retardation, movement disorders, difficulty swallowing, seizures, behavioral problems, progressive problems with development, and an inability to control body temperature.

Diatrizoesaeure Absorption

No information avaliable

Diatrizoesaeure side effects and Toxicity

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Diatrizoesaeure Patient Information

No information avaliable

Diatrizoesaeure Organisms Affected

Humans and other mammals