Acidum diacetylaminotrijodbenzoicum
Brand names,
Acidum diacetylaminotrijodbenzoicum
Analogs
Acidum diacetylaminotrijodbenzoicum
Brand Names Mixture
Acidum diacetylaminotrijodbenzoicum
Chemical_Formula
C9H15N5O3
Acidum diacetylaminotrijodbenzoicum
RX_link
No information avaliable
Acidum diacetylaminotrijodbenzoicum
fda sheet
Acidum diacetylaminotrijodbenzoicum
msds (material safety sheet)
Acidum diacetylaminotrijodbenzoicum
Synthesis Reference
No information avaliable
Acidum diacetylaminotrijodbenzoicum
Molecular Weight
241.247 g/mol
Acidum diacetylaminotrijodbenzoicum
Melting Point
250-255 oC (hydrochloride salt)
Acidum diacetylaminotrijodbenzoicum
H2O Solubility
>20 mg/mL (dichloride salt)
Acidum diacetylaminotrijodbenzoicum
State
Solid
Acidum diacetylaminotrijodbenzoicum
LogP
-1.783
Acidum diacetylaminotrijodbenzoicum
Dosage Forms
No information avaliable
Acidum diacetylaminotrijodbenzoicum
Indication
For the treatment of tetrahydrobiopterin (BH4) deficiency.
Acidum diacetylaminotrijodbenzoicum
Pharmacology
Tetrahydrobiopterin (BH4) is used to convert several amino acids, including phenylalanine, to other essential molecules in the body including neurotransmitters. Tetrahydrobiopterin deficiency can be caused by mutations in GTP cyclohydrolase 1 (GCH1), 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (PCBD1), 6-pyruvoyltetrahydropterin synthase (PTS), and quinoid dihydropteridine reductase (QDPR) genes. These genes make the enzymes that are critical for producing and recycling tetrahydrobiopterin. If one of the enzymes fails to function correctly because of a gene mutation, little or no tetrahydrobiopterin is produced. As a result, phenylalanine from the diet builds up in the bloodstream and other tissues and can damage nerve cells in the brain. High levels of phenylalanine can result in signs and symptoms ranging from temporary low muscle tone to mental retardation, movement disorders, difficulty swallowing, seizures, behavioral problems, progressive problems with development, and an inability to control body temperature.
Acidum diacetylaminotrijodbenzoicum
Absorption
No information avaliable
Acidum diacetylaminotrijodbenzoicum
side effects and Toxicity
No information avaliable
Acidum diacetylaminotrijodbenzoicum
Patient Information
No information avaliable
Acidum diacetylaminotrijodbenzoicum
Organisms Affected
Humans and other mammals