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Vascoray Brand names, Vascoray Analogs

Vascoray Brand Names Mixture

  • No information avaliable

Vascoray Chemical_Formula

C9H15N5O3

Vascoray RX_link

No information avaliable

Vascoray fda sheet

Vascoray msds (material safety sheet)

Vascoray Synthesis Reference

No information avaliable

Vascoray Molecular Weight

241.247 g/mol

Vascoray Melting Point

250-255 oC (hydrochloride salt)

Vascoray H2O Solubility

>20 mg/mL (dichloride salt)

Vascoray State

Solid

Vascoray LogP

-1.783

Vascoray Dosage Forms

No information avaliable

Vascoray Indication

For the treatment of tetrahydrobiopterin (BH4) deficiency.

Vascoray Pharmacology

Tetrahydrobiopterin (BH4) is used to convert several amino acids, including phenylalanine, to other essential molecules in the body including neurotransmitters. Tetrahydrobiopterin deficiency can be caused by mutations in GTP cyclohydrolase 1 (GCH1), 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (PCBD1), 6-pyruvoyltetrahydropterin synthase (PTS), and quinoid dihydropteridine reductase (QDPR) genes. These genes make the enzymes that are critical for producing and recycling tetrahydrobiopterin. If one of the enzymes fails to function correctly because of a gene mutation, little or no tetrahydrobiopterin is produced. As a result, phenylalanine from the diet builds up in the bloodstream and other tissues and can damage nerve cells in the brain. High levels of phenylalanine can result in signs and symptoms ranging from temporary low muscle tone to mental retardation, movement disorders, difficulty swallowing, seizures, behavioral problems, progressive problems with development, and an inability to control body temperature.

Vascoray Absorption

No information avaliable

Vascoray side effects and Toxicity

No information avaliable

Vascoray Patient Information

No information avaliable

Vascoray Organisms Affected

Humans and other mammals