Urovist Cysto Pediatric
Brand names,
Urovist Cysto Pediatric
Analogs
Urovist Cysto Pediatric
Brand Names Mixture
Urovist Cysto Pediatric
Chemical_Formula
C9H15N5O3
Urovist Cysto Pediatric
RX_link
No information avaliable
Urovist Cysto Pediatric
fda sheet
Urovist Cysto Pediatric
msds (material safety sheet)
Urovist Cysto Pediatric
Synthesis Reference
No information avaliable
Urovist Cysto Pediatric
Molecular Weight
241.247 g/mol
Urovist Cysto Pediatric
Melting Point
250-255 oC (hydrochloride salt)
Urovist Cysto Pediatric
H2O Solubility
>20 mg/mL (dichloride salt)
Urovist Cysto Pediatric
State
Solid
Urovist Cysto Pediatric
LogP
-1.783
Urovist Cysto Pediatric
Dosage Forms
No information avaliable
Urovist Cysto Pediatric
Indication
For the treatment of tetrahydrobiopterin (BH4) deficiency.
Urovist Cysto Pediatric
Pharmacology
Tetrahydrobiopterin (BH4) is used to convert several amino acids, including phenylalanine, to other essential molecules in the body including neurotransmitters. Tetrahydrobiopterin deficiency can be caused by mutations in GTP cyclohydrolase 1 (GCH1), 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (PCBD1), 6-pyruvoyltetrahydropterin synthase (PTS), and quinoid dihydropteridine reductase (QDPR) genes. These genes make the enzymes that are critical for producing and recycling tetrahydrobiopterin. If one of the enzymes fails to function correctly because of a gene mutation, little or no tetrahydrobiopterin is produced. As a result, phenylalanine from the diet builds up in the bloodstream and other tissues and can damage nerve cells in the brain. High levels of phenylalanine can result in signs and symptoms ranging from temporary low muscle tone to mental retardation, movement disorders, difficulty swallowing, seizures, behavioral problems, progressive problems with development, and an inability to control body temperature.
Urovist Cysto Pediatric
Absorption
No information avaliable
Urovist Cysto Pediatric
side effects and Toxicity
No information avaliable
Urovist Cysto Pediatric
Patient Information
No information avaliable
Urovist Cysto Pediatric
Organisms Affected
Humans and other mammals