Urovist Sodium 300 en es it fr

Urovist Sodium 300 Brand names, Urovist Sodium 300 Analogs

Urovist Sodium 300 Brand Names Mixture

  • No information avaliable

Urovist Sodium 300 Chemical_Formula

C9H15N5O3

Urovist Sodium 300 RX_link

No information avaliable

Urovist Sodium 300 fda sheet

Urovist Sodium 300 msds (material safety sheet)

Urovist Sodium 300 Synthesis Reference

No information avaliable

Urovist Sodium 300 Molecular Weight

241.247 g/mol

Urovist Sodium 300 Melting Point

250-255 oC (hydrochloride salt)

Urovist Sodium 300 H2O Solubility

>20 mg/mL (dichloride salt)

Urovist Sodium 300 State

Solid

Urovist Sodium 300 LogP

-1.783

Urovist Sodium 300 Dosage Forms

No information avaliable

Urovist Sodium 300 Indication

For the treatment of tetrahydrobiopterin (BH4) deficiency.

Urovist Sodium 300 Pharmacology

Tetrahydrobiopterin (BH4) is used to convert several amino acids, including phenylalanine, to other essential molecules in the body including neurotransmitters. Tetrahydrobiopterin deficiency can be caused by mutations in GTP cyclohydrolase 1 (GCH1), 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (PCBD1), 6-pyruvoyltetrahydropterin synthase (PTS), and quinoid dihydropteridine reductase (QDPR) genes. These genes make the enzymes that are critical for producing and recycling tetrahydrobiopterin. If one of the enzymes fails to function correctly because of a gene mutation, little or no tetrahydrobiopterin is produced. As a result, phenylalanine from the diet builds up in the bloodstream and other tissues and can damage nerve cells in the brain. High levels of phenylalanine can result in signs and symptoms ranging from temporary low muscle tone to mental retardation, movement disorders, difficulty swallowing, seizures, behavioral problems, progressive problems with development, and an inability to control body temperature.

Urovist Sodium 300 Absorption

No information avaliable

Urovist Sodium 300 side effects and Toxicity

No information avaliable

Urovist Sodium 300 Patient Information

No information avaliable

Urovist Sodium 300 Organisms Affected

Humans and other mammals