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Hypaque Brand names, Hypaque Analogs

Hypaque Brand Names Mixture

  • No information avaliable

Hypaque Chemical_Formula


Hypaque RX_link

No information avaliable

Hypaque fda sheet

Hypaque msds (material safety sheet)

Hypaque Synthesis Reference

No information avaliable

Hypaque Molecular Weight

241.247 g/mol

Hypaque Melting Point

250-255 oC (hydrochloride salt)

Hypaque H2O Solubility

>20 mg/mL (dichloride salt)

Hypaque State


Hypaque LogP


Hypaque Dosage Forms

No information avaliable

Hypaque Indication

For the treatment of tetrahydrobiopterin (BH4) deficiency.

Hypaque Pharmacology

Tetrahydrobiopterin (BH4) is used to convert several amino acids, including phenylalanine, to other essential molecules in the body including neurotransmitters. Tetrahydrobiopterin deficiency can be caused by mutations in GTP cyclohydrolase 1 (GCH1), 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (PCBD1), 6-pyruvoyltetrahydropterin synthase (PTS), and quinoid dihydropteridine reductase (QDPR) genes. These genes make the enzymes that are critical for producing and recycling tetrahydrobiopterin. If one of the enzymes fails to function correctly because of a gene mutation, little or no tetrahydrobiopterin is produced. As a result, phenylalanine from the diet builds up in the bloodstream and other tissues and can damage nerve cells in the brain. High levels of phenylalanine can result in signs and symptoms ranging from temporary low muscle tone to mental retardation, movement disorders, difficulty swallowing, seizures, behavioral problems, progressive problems with development, and an inability to control body temperature.

Hypaque Absorption

No information avaliable

Hypaque side effects and Toxicity

No information avaliable

Hypaque Patient Information

No information avaliable

Hypaque Organisms Affected

Humans and other mammals