Angiovist 282 en es it fr

Angiovist 282 Brand names, Angiovist 282 Analogs

Angiovist 282 Brand Names Mixture

  • No information avaliable

Angiovist 282 Chemical_Formula

C9H15N5O3

Angiovist 282 RX_link

No information avaliable

Angiovist 282 fda sheet

Angiovist 282 msds (material safety sheet)

Angiovist 282 Synthesis Reference

No information avaliable

Angiovist 282 Molecular Weight

241.247 g/mol

Angiovist 282 Melting Point

250-255 oC (hydrochloride salt)

Angiovist 282 H2O Solubility

>20 mg/mL (dichloride salt)

Angiovist 282 State

Solid

Angiovist 282 LogP

-1.783

Angiovist 282 Dosage Forms

No information avaliable

Angiovist 282 Indication

For the treatment of tetrahydrobiopterin (BH4) deficiency.

Angiovist 282 Pharmacology

Tetrahydrobiopterin (BH4) is used to convert several amino acids, including phenylalanine, to other essential molecules in the body including neurotransmitters. Tetrahydrobiopterin deficiency can be caused by mutations in GTP cyclohydrolase 1 (GCH1), 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (PCBD1), 6-pyruvoyltetrahydropterin synthase (PTS), and quinoid dihydropteridine reductase (QDPR) genes. These genes make the enzymes that are critical for producing and recycling tetrahydrobiopterin. If one of the enzymes fails to function correctly because of a gene mutation, little or no tetrahydrobiopterin is produced. As a result, phenylalanine from the diet builds up in the bloodstream and other tissues and can damage nerve cells in the brain. High levels of phenylalanine can result in signs and symptoms ranging from temporary low muscle tone to mental retardation, movement disorders, difficulty swallowing, seizures, behavioral problems, progressive problems with development, and an inability to control body temperature.

Angiovist 282 Absorption

No information avaliable

Angiovist 282 side effects and Toxicity

No information avaliable

Angiovist 282 Patient Information

No information avaliable

Angiovist 282 Organisms Affected

Humans and other mammals