PharmacyCodes



Trans-Ddp en es it fr

Trans-Ddp Brand names, Trans-Ddp Analogs

Trans-Ddp Brand Names Mixture

  • No information avaliable

Trans-Ddp Chemical_Formula

Cl2H4N2Pt

Trans-Ddp RX_link

http://www.rxlist.com/cgi/generic3/cisplatin.htm

Trans-Ddp fda sheet

http://www.accessdata.fda.gov/scripts/cder/onctools/summary.cfm?ID=71

Trans-Ddp msds (material safety sheet)

Trans-Ddp MSDS

Trans-Ddp Synthesis Reference

No information avaliable

Trans-Ddp Molecular Weight

298.029 g/mol

Trans-Ddp Melting Point

270 oC

Trans-Ddp H2O Solubility

2530 mg/L

Trans-Ddp State

Solid

Trans-Ddp LogP

-2.19

Trans-Ddp Dosage Forms

Solution

Trans-Ddp Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Trans-Ddp Pharmacology

Cisplatin is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Trans-Ddp Absorption

No information avaliable

Trans-Ddp side effects and Toxicity

No information avaliable

Trans-Ddp Patient Information

No information avaliable

Trans-Ddp Organisms Affected

Humans and other mammals