Dichlorodiammineplatinumiiyelloworangextl en es it fr

Dichlorodiammineplatinumiiyelloworangextl Brand names, Dichlorodiammineplatinumiiyelloworangextl Analogs

Dichlorodiammineplatinumiiyelloworangextl Brand Names Mixture

  • No information avaliable

Dichlorodiammineplatinumiiyelloworangextl Chemical_Formula

Cl2H4N2Pt

Dichlorodiammineplatinumiiyelloworangextl RX_link

http://www.rxlist.com/cgi/generic3/cisplatin.htm

Dichlorodiammineplatinumiiyelloworangextl fda sheet

http://www.accessdata.fda.gov/scripts/cder/onctools/summary.cfm?ID=71

Dichlorodiammineplatinumiiyelloworangextl msds (material safety sheet)

Dichlorodiammineplatinumiiyelloworangextl MSDS

Dichlorodiammineplatinumiiyelloworangextl Synthesis Reference

No information avaliable

Dichlorodiammineplatinumiiyelloworangextl Molecular Weight

298.029 g/mol

Dichlorodiammineplatinumiiyelloworangextl Melting Point

270 oC

Dichlorodiammineplatinumiiyelloworangextl H2O Solubility

2530 mg/L

Dichlorodiammineplatinumiiyelloworangextl State

Solid

Dichlorodiammineplatinumiiyelloworangextl LogP

-2.19

Dichlorodiammineplatinumiiyelloworangextl Dosage Forms

Solution

Dichlorodiammineplatinumiiyelloworangextl Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Dichlorodiammineplatinumiiyelloworangextl Pharmacology

Cisplatin is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Dichlorodiammineplatinumiiyelloworangextl Absorption

No information avaliable

Dichlorodiammineplatinumiiyelloworangextl side effects and Toxicity

No information avaliable

Dichlorodiammineplatinumiiyelloworangextl Patient Information

No information avaliable

Dichlorodiammineplatinumiiyelloworangextl Organisms Affected

Humans and other mammals