PharmacyCodes



Lederplatin en es it fr

Lederplatin Brand names, Lederplatin Analogs

Lederplatin Brand Names Mixture

  • No information avaliable

Lederplatin Chemical_Formula

Cl2H4N2Pt

Lederplatin RX_link

http://www.rxlist.com/cgi/generic3/cisplatin.htm

Lederplatin fda sheet

http://www.accessdata.fda.gov/scripts/cder/onctools/summary.cfm?ID=71

Lederplatin msds (material safety sheet)

Lederplatin MSDS

Lederplatin Synthesis Reference

No information avaliable

Lederplatin Molecular Weight

298.029 g/mol

Lederplatin Melting Point

270 oC

Lederplatin H2O Solubility

2530 mg/L

Lederplatin State

Solid

Lederplatin LogP

-2.19

Lederplatin Dosage Forms

Solution

Lederplatin Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Lederplatin Pharmacology

Cisplatin is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Lederplatin Absorption

No information avaliable

Lederplatin side effects and Toxicity

No information avaliable

Lederplatin Patient Information

No information avaliable

Lederplatin Organisms Affected

Humans and other mammals