Trans-Diamminedichloroplatinum en es it fr

Trans-Diamminedichloroplatinum Brand names, Trans-Diamminedichloroplatinum Analogs

Trans-Diamminedichloroplatinum Brand Names Mixture

  • No information avaliable

Trans-Diamminedichloroplatinum Chemical_Formula


Trans-Diamminedichloroplatinum RX_link

Trans-Diamminedichloroplatinum fda sheet

Trans-Diamminedichloroplatinum msds (material safety sheet)

Trans-Diamminedichloroplatinum MSDS

Trans-Diamminedichloroplatinum Synthesis Reference

No information avaliable

Trans-Diamminedichloroplatinum Molecular Weight

298.029 g/mol

Trans-Diamminedichloroplatinum Melting Point

270 oC

Trans-Diamminedichloroplatinum H2O Solubility

2530 mg/L

Trans-Diamminedichloroplatinum State


Trans-Diamminedichloroplatinum LogP


Trans-Diamminedichloroplatinum Dosage Forms


Trans-Diamminedichloroplatinum Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Trans-Diamminedichloroplatinum Pharmacology

Cisplatin is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Trans-Diamminedichloroplatinum Absorption

No information avaliable

Trans-Diamminedichloroplatinum side effects and Toxicity

No information avaliable

Trans-Diamminedichloroplatinum Patient Information

No information avaliable

Trans-Diamminedichloroplatinum Organisms Affected

Humans and other mammals