PharmacyCodes



Biocisplatinum en es it fr

Biocisplatinum Brand names, Biocisplatinum Analogs

Biocisplatinum Brand Names Mixture

  • No information avaliable

Biocisplatinum Chemical_Formula

Cl2H4N2Pt

Biocisplatinum RX_link

http://www.rxlist.com/cgi/generic3/cisplatin.htm

Biocisplatinum fda sheet

http://www.accessdata.fda.gov/scripts/cder/onctools/summary.cfm?ID=71

Biocisplatinum msds (material safety sheet)

Biocisplatinum MSDS

Biocisplatinum Synthesis Reference

No information avaliable

Biocisplatinum Molecular Weight

298.029 g/mol

Biocisplatinum Melting Point

270 oC

Biocisplatinum H2O Solubility

2530 mg/L

Biocisplatinum State

Solid

Biocisplatinum LogP

-2.19

Biocisplatinum Dosage Forms

Solution

Biocisplatinum Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Biocisplatinum Pharmacology

Cisplatin is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Biocisplatinum Absorption

No information avaliable

Biocisplatinum side effects and Toxicity

No information avaliable

Biocisplatinum Patient Information

No information avaliable

Biocisplatinum Organisms Affected

Humans and other mammals