PharmacyCodes



Cisplatyl en es it fr

Cisplatyl Brand names, Cisplatyl Analogs

Cisplatyl Brand Names Mixture

  • No information avaliable

Cisplatyl Chemical_Formula

Cl2H4N2Pt

Cisplatyl RX_link

http://www.rxlist.com/cgi/generic3/cisplatin.htm

Cisplatyl fda sheet

http://www.accessdata.fda.gov/scripts/cder/onctools/summary.cfm?ID=71

Cisplatyl msds (material safety sheet)

Cisplatyl MSDS

Cisplatyl Synthesis Reference

No information avaliable

Cisplatyl Molecular Weight

298.029 g/mol

Cisplatyl Melting Point

270 oC

Cisplatyl H2O Solubility

2530 mg/L

Cisplatyl State

Solid

Cisplatyl LogP

-2.19

Cisplatyl Dosage Forms

Solution

Cisplatyl Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Cisplatyl Pharmacology

Cisplatin is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Cisplatyl Absorption

No information avaliable

Cisplatyl side effects and Toxicity

No information avaliable

Cisplatyl Patient Information

No information avaliable

Cisplatyl Organisms Affected

Humans and other mammals