Platinum Ammine Chloride
Platinum Ammine Chloride Brand names, Platinum Ammine Chloride Analogs
- Abiplatin
- Biocisplatinum
- Briplatin
- CACP
- CPDC
- CPDD
- Carboquone
- Cis Pt Ii
- Cis-Ddp
- Cis-Diaminedichloroplatinum
- Cis-Diamminedichloroplatinum
- Cismaplat
- Cisplatine
- Cisplatyl
- Citoplationo
- DDP
- Ddpt
- Diamminedichloroplatinum
- Dichlorodiammineplatinumiiyelloworangextl
- Lederplatin
- Neoplatin
- Plastin
- Platamine
- Platiblastin
- Platidiam
- Platinex
- Platinol
- Platinol-Aq
- Platinoxan
- Platinum Ammine Chloride
- Platinum Ammonium Chloride
- Platinum Diamine Dichloride
- Randa
- Trans-Ddp
- Trans-Diaminedichloroplatinum
- Trans-Diamminedichloroplatinum
- Trans-Dichlorodiammine Platinum
- Trans-Platinumdiammine Dichloride
Platinum Ammine Chloride Brand Names Mixture
- No information avaliable
Platinum Ammine Chloride Chemical_Formula
Cl2H4N2Pt
Platinum Ammine Chloride RX_link
http://www.rxlist.com/cgi/generic3/cisplatin.htm
Platinum Ammine Chloride fda sheet
Platinum Ammine Chloride msds (material safety sheet)
Platinum Ammine Chloride Synthesis Reference
No information avaliable
Platinum Ammine Chloride Molecular Weight
298.029 g/mol
Platinum Ammine Chloride Melting Point
270 oC
Platinum Ammine Chloride H2O Solubility
2530 mg/L
Platinum Ammine Chloride State
Solid
Platinum Ammine Chloride LogP
-2.19
Platinum Ammine Chloride Dosage Forms
Solution
Platinum Ammine Chloride Indication
For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.
Platinum Ammine Chloride Pharmacology
Cisplatin is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.
Platinum Ammine Chloride Absorption
No information avaliable
Platinum Ammine Chloride side effects and Toxicity
No information avaliable
Platinum Ammine Chloride Patient Information
No information avaliable
Platinum Ammine Chloride Organisms Affected
Humans and other mammals
