Platinum Ammine Chloride en es it fr

Platinum Ammine Chloride Brand names, Platinum Ammine Chloride Analogs

Platinum Ammine Chloride Brand Names Mixture

  • No information avaliable

Platinum Ammine Chloride Chemical_Formula

Cl2H4N2Pt

Platinum Ammine Chloride RX_link

http://www.rxlist.com/cgi/generic3/cisplatin.htm

Platinum Ammine Chloride fda sheet

http://www.accessdata.fda.gov/scripts/cder/onctools/summary.cfm?ID=71

Platinum Ammine Chloride msds (material safety sheet)

Platinum_Ammine_Chloride MSDS

Platinum Ammine Chloride Synthesis Reference

No information avaliable

Platinum Ammine Chloride Molecular Weight

298.029 g/mol

Platinum Ammine Chloride Melting Point

270 oC

Platinum Ammine Chloride H2O Solubility

2530 mg/L

Platinum Ammine Chloride State

Solid

Platinum Ammine Chloride LogP

-2.19

Platinum Ammine Chloride Dosage Forms

Solution

Platinum Ammine Chloride Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Platinum Ammine Chloride Pharmacology

Cisplatin is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Platinum Ammine Chloride Absorption

No information avaliable

Platinum Ammine Chloride side effects and Toxicity

No information avaliable

Platinum Ammine Chloride Patient Information

No information avaliable

Platinum Ammine Chloride Organisms Affected

Humans and other mammals