Trans-Diaminedichloroplatinum en es it fr

Trans-Diaminedichloroplatinum Brand names, Trans-Diaminedichloroplatinum Analogs

Trans-Diaminedichloroplatinum Brand Names Mixture

  • No information avaliable

Trans-Diaminedichloroplatinum Chemical_Formula


Trans-Diaminedichloroplatinum RX_link

Trans-Diaminedichloroplatinum fda sheet

Trans-Diaminedichloroplatinum msds (material safety sheet)

Trans-Diaminedichloroplatinum MSDS

Trans-Diaminedichloroplatinum Synthesis Reference

No information avaliable

Trans-Diaminedichloroplatinum Molecular Weight

298.029 g/mol

Trans-Diaminedichloroplatinum Melting Point

270 oC

Trans-Diaminedichloroplatinum H2O Solubility

2530 mg/L

Trans-Diaminedichloroplatinum State


Trans-Diaminedichloroplatinum LogP


Trans-Diaminedichloroplatinum Dosage Forms


Trans-Diaminedichloroplatinum Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Trans-Diaminedichloroplatinum Pharmacology

Cisplatin is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Trans-Diaminedichloroplatinum Absorption

No information avaliable

Trans-Diaminedichloroplatinum side effects and Toxicity

No information avaliable

Trans-Diaminedichloroplatinum Patient Information

No information avaliable

Trans-Diaminedichloroplatinum Organisms Affected

Humans and other mammals