PharmacyCodes



Abiplatin en es it fr

Abiplatin Brand names, Abiplatin Analogs

Abiplatin Brand Names Mixture

  • No information avaliable

Abiplatin Chemical_Formula

Cl2H4N2Pt

Abiplatin RX_link

http://www.rxlist.com/cgi/generic3/cisplatin.htm

Abiplatin fda sheet

http://www.accessdata.fda.gov/scripts/cder/onctools/summary.cfm?ID=71

Abiplatin msds (material safety sheet)

Abiplatin MSDS

Abiplatin Synthesis Reference

No information avaliable

Abiplatin Molecular Weight

298.029 g/mol

Abiplatin Melting Point

270 oC

Abiplatin H2O Solubility

2530 mg/L

Abiplatin State

Solid

Abiplatin LogP

-2.19

Abiplatin Dosage Forms

Solution

Abiplatin Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Abiplatin Pharmacology

Cisplatin is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Abiplatin Absorption

No information avaliable

Abiplatin side effects and Toxicity

No information avaliable

Abiplatin Patient Information

No information avaliable

Abiplatin Organisms Affected

Humans and other mammals