Trans-Platinumdiammine Dichloride
Trans-Platinumdiammine Dichloride Brand names, Trans-Platinumdiammine Dichloride Analogs
- Abiplatin
- Biocisplatinum
- Briplatin
- CACP
- CPDC
- CPDD
- Carboquone
- Cis Pt Ii
- Cis-Ddp
- Cis-Diaminedichloroplatinum
- Cis-Diamminedichloroplatinum
- Cismaplat
- Cisplatine
- Cisplatyl
- Citoplationo
- DDP
- Ddpt
- Diamminedichloroplatinum
- Dichlorodiammineplatinumiiyelloworangextl
- Lederplatin
- Neoplatin
- Plastin
- Platamine
- Platiblastin
- Platidiam
- Platinex
- Platinol
- Platinol-Aq
- Platinoxan
- Platinum Ammine Chloride
- Platinum Ammonium Chloride
- Platinum Diamine Dichloride
- Randa
- Trans-Ddp
- Trans-Diaminedichloroplatinum
- Trans-Diamminedichloroplatinum
- Trans-Dichlorodiammine Platinum
- Trans-Platinumdiammine Dichloride
Trans-Platinumdiammine Dichloride Brand Names Mixture
- No information avaliable
Trans-Platinumdiammine Dichloride Chemical_Formula
Cl2H4N2Pt
Trans-Platinumdiammine Dichloride RX_link
http://www.rxlist.com/cgi/generic3/cisplatin.htm
Trans-Platinumdiammine Dichloride fda sheet
Trans-Platinumdiammine Dichloride msds (material safety sheet)
Trans-Platinumdiammine Dichloride Synthesis Reference
No information avaliable
Trans-Platinumdiammine Dichloride Molecular Weight
298.029 g/mol
Trans-Platinumdiammine Dichloride Melting Point
270 oC
Trans-Platinumdiammine Dichloride H2O Solubility
2530 mg/L
Trans-Platinumdiammine Dichloride State
Solid
Trans-Platinumdiammine Dichloride LogP
-2.19
Trans-Platinumdiammine Dichloride Dosage Forms
Solution
Trans-Platinumdiammine Dichloride Indication
For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.
Trans-Platinumdiammine Dichloride Pharmacology
Cisplatin is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.
Trans-Platinumdiammine Dichloride Absorption
No information avaliable
Trans-Platinumdiammine Dichloride side effects and Toxicity
No information avaliable
Trans-Platinumdiammine Dichloride Patient Information
No information avaliable
Trans-Platinumdiammine Dichloride Organisms Affected
Humans and other mammals
