Trans-Platinumdiammine Dichloride en es it fr

Trans-Platinumdiammine Dichloride Brand names, Trans-Platinumdiammine Dichloride Analogs

Trans-Platinumdiammine Dichloride Brand Names Mixture

  • No information avaliable

Trans-Platinumdiammine Dichloride Chemical_Formula

Cl2H4N2Pt

Trans-Platinumdiammine Dichloride RX_link

http://www.rxlist.com/cgi/generic3/cisplatin.htm

Trans-Platinumdiammine Dichloride fda sheet

http://www.accessdata.fda.gov/scripts/cder/onctools/summary.cfm?ID=71

Trans-Platinumdiammine Dichloride msds (material safety sheet)

Trans-Platinumdiammine_Dichloride MSDS

Trans-Platinumdiammine Dichloride Synthesis Reference

No information avaliable

Trans-Platinumdiammine Dichloride Molecular Weight

298.029 g/mol

Trans-Platinumdiammine Dichloride Melting Point

270 oC

Trans-Platinumdiammine Dichloride H2O Solubility

2530 mg/L

Trans-Platinumdiammine Dichloride State

Solid

Trans-Platinumdiammine Dichloride LogP

-2.19

Trans-Platinumdiammine Dichloride Dosage Forms

Solution

Trans-Platinumdiammine Dichloride Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Trans-Platinumdiammine Dichloride Pharmacology

Cisplatin is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Trans-Platinumdiammine Dichloride Absorption

No information avaliable

Trans-Platinumdiammine Dichloride side effects and Toxicity

No information avaliable

Trans-Platinumdiammine Dichloride Patient Information

No information avaliable

Trans-Platinumdiammine Dichloride Organisms Affected

Humans and other mammals