PharmacyCodes



Cis Pt Ii en es it fr

Cis Pt Ii Brand names, Cis Pt Ii Analogs

Cis Pt Ii Brand Names Mixture

  • No information avaliable

Cis Pt Ii Chemical_Formula

Cl2H4N2Pt

Cis Pt Ii RX_link

http://www.rxlist.com/cgi/generic3/cisplatin.htm

Cis Pt Ii fda sheet

http://www.accessdata.fda.gov/scripts/cder/onctools/summary.cfm?ID=71

Cis Pt Ii msds (material safety sheet)

Cis_Pt_Ii MSDS

Cis Pt Ii Synthesis Reference

No information avaliable

Cis Pt Ii Molecular Weight

298.029 g/mol

Cis Pt Ii Melting Point

270 oC

Cis Pt Ii H2O Solubility

2530 mg/L

Cis Pt Ii State

Solid

Cis Pt Ii LogP

-2.19

Cis Pt Ii Dosage Forms

Solution

Cis Pt Ii Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Cis Pt Ii Pharmacology

Cisplatin is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Cis Pt Ii Absorption

No information avaliable

Cis Pt Ii side effects and Toxicity

No information avaliable

Cis Pt Ii Patient Information

No information avaliable

Cis Pt Ii Organisms Affected

Humans and other mammals