PharmacyCodes



Platiblastin en es it fr

Platiblastin Brand names, Platiblastin Analogs

Platiblastin Brand Names Mixture

  • No information avaliable

Platiblastin Chemical_Formula

Cl2H4N2Pt

Platiblastin RX_link

http://www.rxlist.com/cgi/generic3/cisplatin.htm

Platiblastin fda sheet

http://www.accessdata.fda.gov/scripts/cder/onctools/summary.cfm?ID=71

Platiblastin msds (material safety sheet)

Platiblastin MSDS

Platiblastin Synthesis Reference

No information avaliable

Platiblastin Molecular Weight

298.029 g/mol

Platiblastin Melting Point

270 oC

Platiblastin H2O Solubility

2530 mg/L

Platiblastin State

Solid

Platiblastin LogP

-2.19

Platiblastin Dosage Forms

Solution

Platiblastin Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Platiblastin Pharmacology

Cisplatin is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Platiblastin Absorption

No information avaliable

Platiblastin side effects and Toxicity

No information avaliable

Platiblastin Patient Information

No information avaliable

Platiblastin Organisms Affected

Humans and other mammals