PharmacyCodes



Cismaplat en es it fr

Cismaplat Brand names, Cismaplat Analogs

Cismaplat Brand Names Mixture

  • No information avaliable

Cismaplat Chemical_Formula

Cl2H4N2Pt

Cismaplat RX_link

http://www.rxlist.com/cgi/generic3/cisplatin.htm

Cismaplat fda sheet

http://www.accessdata.fda.gov/scripts/cder/onctools/summary.cfm?ID=71

Cismaplat msds (material safety sheet)

Cismaplat MSDS

Cismaplat Synthesis Reference

No information avaliable

Cismaplat Molecular Weight

298.029 g/mol

Cismaplat Melting Point

270 oC

Cismaplat H2O Solubility

2530 mg/L

Cismaplat State

Solid

Cismaplat LogP

-2.19

Cismaplat Dosage Forms

Solution

Cismaplat Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Cismaplat Pharmacology

Cisplatin is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Cismaplat Absorption

No information avaliable

Cismaplat side effects and Toxicity

No information avaliable

Cismaplat Patient Information

No information avaliable

Cismaplat Organisms Affected

Humans and other mammals