Cis-Diaminedichloroplatinum en es it fr

Cis-Diaminedichloroplatinum Brand names, Cis-Diaminedichloroplatinum Analogs

Cis-Diaminedichloroplatinum Brand Names Mixture

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Cis-Diaminedichloroplatinum Chemical_Formula


Cis-Diaminedichloroplatinum RX_link

Cis-Diaminedichloroplatinum fda sheet

Cis-Diaminedichloroplatinum msds (material safety sheet)

Cis-Diaminedichloroplatinum MSDS

Cis-Diaminedichloroplatinum Synthesis Reference

No information avaliable

Cis-Diaminedichloroplatinum Molecular Weight

298.029 g/mol

Cis-Diaminedichloroplatinum Melting Point

270 oC

Cis-Diaminedichloroplatinum H2O Solubility

2530 mg/L

Cis-Diaminedichloroplatinum State


Cis-Diaminedichloroplatinum LogP


Cis-Diaminedichloroplatinum Dosage Forms


Cis-Diaminedichloroplatinum Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Cis-Diaminedichloroplatinum Pharmacology

Cisplatin is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Cis-Diaminedichloroplatinum Absorption

No information avaliable

Cis-Diaminedichloroplatinum side effects and Toxicity

No information avaliable

Cis-Diaminedichloroplatinum Patient Information

No information avaliable

Cis-Diaminedichloroplatinum Organisms Affected

Humans and other mammals