PharmacyCodes



Citoplationo en es it fr

Citoplationo Brand names, Citoplationo Analogs

Citoplationo Brand Names Mixture

  • No information avaliable

Citoplationo Chemical_Formula

Cl2H4N2Pt

Citoplationo RX_link

http://www.rxlist.com/cgi/generic3/cisplatin.htm

Citoplationo fda sheet

http://www.accessdata.fda.gov/scripts/cder/onctools/summary.cfm?ID=71

Citoplationo msds (material safety sheet)

Citoplationo MSDS

Citoplationo Synthesis Reference

No information avaliable

Citoplationo Molecular Weight

298.029 g/mol

Citoplationo Melting Point

270 oC

Citoplationo H2O Solubility

2530 mg/L

Citoplationo State

Solid

Citoplationo LogP

-2.19

Citoplationo Dosage Forms

Solution

Citoplationo Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Citoplationo Pharmacology

Cisplatin is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Citoplationo Absorption

No information avaliable

Citoplationo side effects and Toxicity

No information avaliable

Citoplationo Patient Information

No information avaliable

Citoplationo Organisms Affected

Humans and other mammals