PharmacyCodes



Platinoxan en es it fr

Platinoxan Brand names, Platinoxan Analogs

Platinoxan Brand Names Mixture

  • No information avaliable

Platinoxan Chemical_Formula

Cl2H4N2Pt

Platinoxan RX_link

http://www.rxlist.com/cgi/generic3/cisplatin.htm

Platinoxan fda sheet

http://www.accessdata.fda.gov/scripts/cder/onctools/summary.cfm?ID=71

Platinoxan msds (material safety sheet)

Platinoxan MSDS

Platinoxan Synthesis Reference

No information avaliable

Platinoxan Molecular Weight

298.029 g/mol

Platinoxan Melting Point

270 oC

Platinoxan H2O Solubility

2530 mg/L

Platinoxan State

Solid

Platinoxan LogP

-2.19

Platinoxan Dosage Forms

Solution

Platinoxan Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Platinoxan Pharmacology

Cisplatin is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Platinoxan Absorption

No information avaliable

Platinoxan side effects and Toxicity

No information avaliable

Platinoxan Patient Information

No information avaliable

Platinoxan Organisms Affected

Humans and other mammals