PharmacyCodes



Platidiam en es it fr

Platidiam Brand names, Platidiam Analogs

Platidiam Brand Names Mixture

  • No information avaliable

Platidiam Chemical_Formula

Cl2H4N2Pt

Platidiam RX_link

http://www.rxlist.com/cgi/generic3/cisplatin.htm

Platidiam fda sheet

http://www.accessdata.fda.gov/scripts/cder/onctools/summary.cfm?ID=71

Platidiam msds (material safety sheet)

Platidiam MSDS

Platidiam Synthesis Reference

No information avaliable

Platidiam Molecular Weight

298.029 g/mol

Platidiam Melting Point

270 oC

Platidiam H2O Solubility

2530 mg/L

Platidiam State

Solid

Platidiam LogP

-2.19

Platidiam Dosage Forms

Solution

Platidiam Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Platidiam Pharmacology

Cisplatin is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Platidiam Absorption

No information avaliable

Platidiam side effects and Toxicity

No information avaliable

Platidiam Patient Information

No information avaliable

Platidiam Organisms Affected

Humans and other mammals