Platinum Ammonium Chloride en es it fr

Platinum Ammonium Chloride Brand names, Platinum Ammonium Chloride Analogs

Platinum Ammonium Chloride Brand Names Mixture

  • No information avaliable

Platinum Ammonium Chloride Chemical_Formula

Cl2H4N2Pt

Platinum Ammonium Chloride RX_link

http://www.rxlist.com/cgi/generic3/cisplatin.htm

Platinum Ammonium Chloride fda sheet

http://www.accessdata.fda.gov/scripts/cder/onctools/summary.cfm?ID=71

Platinum Ammonium Chloride msds (material safety sheet)

Platinum_Ammonium_Chloride MSDS

Platinum Ammonium Chloride Synthesis Reference

No information avaliable

Platinum Ammonium Chloride Molecular Weight

298.029 g/mol

Platinum Ammonium Chloride Melting Point

270 oC

Platinum Ammonium Chloride H2O Solubility

2530 mg/L

Platinum Ammonium Chloride State

Solid

Platinum Ammonium Chloride LogP

-2.19

Platinum Ammonium Chloride Dosage Forms

Solution

Platinum Ammonium Chloride Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Platinum Ammonium Chloride Pharmacology

Cisplatin is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Platinum Ammonium Chloride Absorption

No information avaliable

Platinum Ammonium Chloride side effects and Toxicity

No information avaliable

Platinum Ammonium Chloride Patient Information

No information avaliable

Platinum Ammonium Chloride Organisms Affected

Humans and other mammals