Diamminedichloroplatinum en es it fr

Diamminedichloroplatinum Brand names, Diamminedichloroplatinum Analogs

Diamminedichloroplatinum Brand Names Mixture

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Diamminedichloroplatinum Chemical_Formula


Diamminedichloroplatinum RX_link


Diamminedichloroplatinum fda sheet


Diamminedichloroplatinum msds (material safety sheet)

Diamminedichloroplatinum MSDS

Diamminedichloroplatinum Synthesis Reference

No information avaliable

Diamminedichloroplatinum Molecular Weight

298.029 g/mol

Diamminedichloroplatinum Melting Point

270 oC

Diamminedichloroplatinum H2O Solubility

2530 mg/L

Diamminedichloroplatinum State


Diamminedichloroplatinum LogP


Diamminedichloroplatinum Dosage Forms


Diamminedichloroplatinum Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Diamminedichloroplatinum Pharmacology

Cisplatin is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Diamminedichloroplatinum Absorption

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Diamminedichloroplatinum side effects and Toxicity

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Diamminedichloroplatinum Patient Information

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Diamminedichloroplatinum Organisms Affected

Humans and other mammals