Diamminedichloroplatinum
Diamminedichloroplatinum Brand names, Diamminedichloroplatinum Analogs
- Abiplatin
- Biocisplatinum
- Briplatin
- CACP
- CPDC
- CPDD
- Carboquone
- Cis Pt Ii
- Cis-Ddp
- Cis-Diaminedichloroplatinum
- Cis-Diamminedichloroplatinum
- Cismaplat
- Cisplatine
- Cisplatyl
- Citoplationo
- DDP
- Ddpt
- Diamminedichloroplatinum
- Dichlorodiammineplatinumiiyelloworangextl
- Lederplatin
- Neoplatin
- Plastin
- Platamine
- Platiblastin
- Platidiam
- Platinex
- Platinol
- Platinol-Aq
- Platinoxan
- Platinum Ammine Chloride
- Platinum Ammonium Chloride
- Platinum Diamine Dichloride
- Randa
- Trans-Ddp
- Trans-Diaminedichloroplatinum
- Trans-Diamminedichloroplatinum
- Trans-Dichlorodiammine Platinum
- Trans-Platinumdiammine Dichloride
Diamminedichloroplatinum Brand Names Mixture
- No information avaliable
Diamminedichloroplatinum Chemical_Formula
Cl2H4N2Pt
Diamminedichloroplatinum RX_link
http://www.rxlist.com/cgi/generic3/cisplatin.htm
Diamminedichloroplatinum fda sheet
Diamminedichloroplatinum msds (material safety sheet)
Diamminedichloroplatinum Synthesis Reference
No information avaliable
Diamminedichloroplatinum Molecular Weight
298.029 g/mol
Diamminedichloroplatinum Melting Point
270 oC
Diamminedichloroplatinum H2O Solubility
2530 mg/L
Diamminedichloroplatinum State
Solid
Diamminedichloroplatinum LogP
-2.19
Diamminedichloroplatinum Dosage Forms
Solution
Diamminedichloroplatinum Indication
For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.
Diamminedichloroplatinum Pharmacology
Cisplatin is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.
Diamminedichloroplatinum Absorption
No information avaliable
Diamminedichloroplatinum side effects and Toxicity
No information avaliable
Diamminedichloroplatinum Patient Information
No information avaliable
Diamminedichloroplatinum Organisms Affected
Humans and other mammals
