D-Oxamicina
Brand names,
D-Oxamicina
Analogs
D-Oxamicina
Brand Names Mixture
D-Oxamicina
Chemical_Formula
C3H6N2O2
D-Oxamicina
RX_link
No information avaliable
D-Oxamicina
fda sheet
D-Oxamicina
msds (material safety sheet)
D-Oxamicina
Synthesis Reference
No information avaliable
D-Oxamicina
Molecular Weight
102.092 g/mol
D-Oxamicina
Melting Point
147 oC
D-Oxamicina
H2O Solubility
Soluble
D-Oxamicina
State
Solid
D-Oxamicina
LogP
-1.631
D-Oxamicina
Dosage Forms
Capsules (red and gray capsules, oral, 250mg)
D-Oxamicina
Indication
Used in combination with up to 5 other drugs as a treatment for Mycobacterium avium complex (MAC) and is also used to treat tuberculosis (TB).
D-Oxamicina
Pharmacology
Cycloserine, a broad-spectrum antibiotic, may be bactericidal or bacteriostatic, depending on its concentration at the site of infection and the susceptibility of the organism. Cycloserine works by blocking the formation of these peptidoglycans. By doing this the walls of the bacteria become weak and it results in the death of the bacteria
D-Oxamicina
Absorption
Rapidly and almost completely absorbed (70 to 90%) from the gastrointestinal tract following oral administration.
D-Oxamicina
side effects and Toxicity
Oral LD50 in mouse is 5290 mg/kg, and in rat is over 5000 mg/kg. Symptoms of a cycloserine overdose include drowsiness, confusion, headache, dizziness, irritability, numbness and tingling, difficulty speaking, paralysis, abnormal behavior, seizures, and unconsciousness.
D-Oxamicina
Patient Information
D-Oxamicina
Organisms Affected
Enteric bacteria and other eubacteria